Table of Contents
Both ZMA and ZMB are dietary supplements that are especially popular among athletes. They most often promise anabolic effects through the promotion of healthy testosterone levels, athletic performance and quality sleep. Behind the effects of these synergistic formulas is a trio of micronutrients in the form of zinc, magnesium and vitamin B6. These play a key role in a number of bodily functions related to immunity, muscle function and overall health. In this article you will learn, among other things, what the individual substances contained in ZMA and ZMB are and why athletes and those who are less active should watch their intake.
In this article you will read about the influence of ZMA and ZMB on these specific areas:
What is ZMA?
As you already know, ZMA j is a dietary supplement containing zinc, magnesium and vitamin B6. However, SNAC Nutrition’s original formulation specifically has zinc monomethionine aspartate, magnesium aspartate, and pyridoxine hydrochloride (vitamin B6) in the formula. You may also come across the name zinc magnesium aspartate. However, this mixture has a trademark. [1]
What is the composition of ZMA?
One dose of this supplement usually contains [2]:
- 30 mg of zinc monomethionine aspartate
- 450 mg of magnesium aspartate
- 10.5 mg pyridoxine hydrochloride
This original formula has a trademark. However, you can also find ZMA on the market from other manufacturers with a different composition. The differences are both in the forms of zinc or magnesium, as well as in the amount of active ingredients in the one dose. [3]
What is ZMB?
In the ingredients list of supplements called ZMB or ZMB6 you can also find zinc, magnesium and vitamin B6. Thanks to this, they also have similar effects on health and sports performance.
What is the difference between ZMA and ZMB?
The main difference is in the name of these supplements. ZMA with the registered trademark has the exact composition that we have listed above. In the case of ZMB, manufacturers have more freedom. Therefore, you need to always check the composition to see if it suits your requirements. Each supplement with this name may have been formulated slightly differently.
6. Other effects of ZMA and ZMB
The ZMA complex or the individual substances it contains have also been studied in other areas. However, these effects are not yet proven.
- Weight loss: Obese people who took 30 mg of zinc daily lost slightly more weight in a month than study participants without supplementation. [32]
- Muscle growth: In addition to supporting anabolic hormones, zinc can also act directly on muscle building. In fact, scientists have found that it has an effect on muscle cell activation and growth. As a result, it may contribute to the actual formation and regeneration of muscle mass. [35]
- Blood sugar level control: According to some studies, taking zinc and magnesium can support the function of the hormone insulin and maintain more stable blood sugar levels. [33–34]
How should you take ZMA and ZMB?
ZMA or ZMB6 supplements are an option to conveniently take all 3 substances, i.e. zinc, magnesium a vitamin B6 in one supplement. Each product has its own recommended dosage and usage, which may vary slightly between manufacturers.
However, most recommend taking a dose of ZMA 30-60 minutes before sleep. However, beware of taking it together with supplements or food containing calcium, which can impair zinc absorption. [29]
Does ZMA or ZMB have any side effects?
No adverse effects have been observed in healthy people when recommended use is followed. However, beware of combining it with other dietary supplements, since in ZMA, depending on the specific product, you are likely to be consuming the daily dose of zinc, magnesium or vitamin B6.
What should you remember?
ZMA or ZMB6 is a supplement with a wide range of effects that will be appreciated by everyone, especially athletes. Thanks to its zinc, magnesium and vitamin B6 content, it supports the maintenance of healthy testosterone levels, sports performance, but also quality sleep and immune function. For maximum effect, this supplement should be taken before bedtime.
Did you learn anything new and interesting from this article? Please don’t forget to share it with your friends.
[1] Solomon, T. ZMA Research Analysis. – https://examine.com/supplements/zma/
[2] SNAC Nutrition. The Truth about the Original ZMA® Research. – https://snac.com/blogs/blog/the-truth-about-the-original-zma-research
[3] Schepis, J. ALL ABOUT ZMA. – https://www.jpshealthandfitness.com.au/all-about-zma/
[4] King, J. C., Brown, K. H., Gibson, R. S., Krebs, N. F., Lowe, N. M., Siekmann, J. H., & Raiten, D. J. Biomarkers of Nutrition for Development (BOND)—Zinc Review. – https://doi.org/10.3945/jn.115.220079
[5] Frank, K., Patel, K., Lopez, G., & Willis, B. Zinc Research Analysis. – https://examine.com/supplements/zinc/research/
[6] EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of health claims related to zinc. – https://doi.org/10.2903/j.efsa.2010.1819
[7] Thorne. How Lack of Magnesium Impacts Athletes. – https://www.thorne.com/take-5-daily/article/how-lack-of-magnesium-impacts-athletes
[8] Bailey, C. Magnesium. Why it can help Performance. – https://www.christinebailey.co.uk/magnesium-the-essential-mineral-for-athletes/
[9] Sports Performance Bulletin. Why magnesium matters to athletes. – https://www.sportsperformancebulletin.com/nutrition-for-endurance-athletes/supplements/magnesium-matters-athletes/
[10] S, H. S., hu, & MD. Osteoporosis: Calcium and Magnesium. – https://www.spineuniverse.com/conditions/osteoporosis/osteoporosis-calcium-magnesium
[11] Kass, L. S., & Poeira, F. The effect of acute vs chronic magnesium supplementation on exercise and recovery on resistance exercise, blood pressure and total peripheral resistance on normotensive adults. – https://doi.org/10.1186/s12970-015-0081-z
[12] Psychology Today. What You Need to Know About Magnesium and Your Sleep.– https://www.psychologytoday.com/us/blog/sleep-newzzz/201805/what-you-need-know-about-magnesium-and-your-sleep
[13] Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
[14] Psychology Today. Magnesium and the Brain: The Original Chill Pill. – https://www.psychologytoday.com/us/blog/evolutionary-psychiatry/201106/magnesium-and-the-brain-the-original-chill-pill
[15] EFSA. Magnesium related health claims. – https://www.efsa.europa.eu/en/efsajournal/pub/1807
[16] Noah, L., Dye, L., Bois De Fer, B., Mazur, A., Pickering, G., & Pouteau, E. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial. – https://doi.org/10.1002/smi.3051
[17] Seelig, M. S. Auto-immune complications of D-penicillamine—A possible result of zinc and magnesium depletion and of pyridoxine inactivation. – https://doi.org/10.1080/07315724.1982.10718989
[18] Noah, L., Pickering, G., Mazur, A., Dubray, C., Hitier, S., Dualé, C., & Pouteau, E. Impact of magnesium supplementation, in combination with vitamin B6, on stress and magnesium status: Secondary data from a randomized controlled trial. – https://doi.org/10.1684/mrh.2020.0468
[19] De Souza, M. C., Walker, A. F., Robinson, P. A., & Bolland, K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: A randomized, double-blind, crossover study. – https://doi.org/10.1089/152460900318623
[20] Examine. 5 nutrients that could lift your mood. – https://examine.com/articles/5-nutrients-to-lift-mood/
[21] Jadidi, A., Rezaei Ashtiani, A., Khanmohamadi Hezaveh, A., & Aghaepour, S. M. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: A randomized controlled clinical trial. – https://doi.org/10.1186/s12906-022-03814-8
[22] Lemoine, P., Bablon, J.-C., & Da Silva, C. A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study. – https://doi.org/10.1016/j.ctim.2019.05.024
[23] Saito, H., Cherasse, Y., Suzuki, R., Mitarai, M., Ueda, F., & Urade, Y. Zinc-rich oysters as well as zinc-yeast- and astaxanthin-enriched food improved sleep efficiency and sleep onset in a randomized controlled trial of healthy individuals. – https://doi.org/10.1002/mnfr.201600882
[24] Kawai, N., Sakai, N., Okuro, M., Karakawa, S., Tsuneyoshi, Y., Kawasaki, N., Takeda, T., Bannai, M., & Nishino, S. The Sleep-Promoting and Hypothermic Effects of Glycine are Mediated by NMDA Receptors in the Suprachiasmatic Nucleus. – https://doi.org/10.1038/npp.2014.326
[25] Human Kinetics. The role of zinc in athletic performance. – https://us.humankinetics.com/blogs/excerpt/the-role-of-zinc-in-athletic-performance
[26] Examine. How can you increase testosterone naturally?– https://examine.com/articles/increase-testosterone-naturally/
[27] Baltaci, A. K., Mogulkoc, R., & Baltaci, S. B. Review: The role of zinc in the endocrine system.
[28] EFSA. Vitamin B6 related health claims. – https://www.efsa.europa.eu/en/efsajournal/pub/1225
[29] D. S. J. M. L. Do ZMA supplements really work? – https://patient.info/news-and-features/do-zma-supplements-really-work
[30] Kumrungsee, T., Zhang, P., Chartkul, M., Yanaka, N., & Kato, N. Potential Role of Vitamin B6 in Ameliorating the Severity of COVID-19 and Its Complications. – https://doi.org/10.3389/fnut.2020.562051
[31] Mikkelsen, K., Dargahi, N., Fraser, S., & Apostolopoulos, V. High-Dose Vitamin B6 (Pyridoxine) Displays Strong Anti-Inflammatory Properties in Lipopolysaccharide-Stimulated Monocytes. – https://doi.org/10.3390/biomedicines11092578
[32] L, P., A, O., M, M., Y, K. B., N, F., M, A. J., & S, M. Effects of zinc supplementation on the anthropometric measurements, lipid profiles and fasting blood glucose in the healthy obese adults. – https://doi.org/10.5681/apb.2013.027
[33] Morais, J. B. S., Severo, J. S., de Alencar, G. R. R., de Oliveira, A. R. S., Cruz, K. J. C., Marreiro, D. do N., Freitas, B. de J. E. S. de A., de Carvalho, C. M. R., Martins, M. do C. de C. E., & Frota, K. de M. G. Effect of magnesium supplementation on insulin resistance in humans: A systematic review. – https://doi.org/10.1016/j.nut.2017.01.009
[34] Jayawardena, R., Ranasinghe, P., Galappatthy, P., Malkanthi, R., Constantine, G., & Katulanda, P. Effects of zinc supplementation on diabetes mellitus: A systematic review and meta-analysis. – https://doi.org/10.1186/1758-5996-4-13
[35] Hernández-Camacho, J. D., Vicente-García, C., Parsons, D. S., & Navas-Enamorado, I. Zinc at the crossroads of exercise and proteostasis. – https://doi.org/10.1016/j.redox.2020.101529
[36] Effects of a novel zinc-magnesium formulation on hormones and strength – https://www.researchgate.net/publication/288406212_Effects_of_a_novel_zinc-magnesium_formulation_on_hormones_and_strength
Leave a Reply
You must be logged in to post a comment.